Monkeypox epidemic in brief as of June 10, 2022

Since May 13, 2022, the World Health Organization has reported cases of monkeypox or monkeypox from 28 member countries in four WHO regions (Region of the Americas, Europe, Eastern Mediterranean and Western Pacific regions) where monkeypox is not present. Common or not previously reported.

As epidemiological investigations continue, most cases reported in newly affected countries have come through sexual or other health services in primary or secondary care settings, with a history of travel to countries in Europe and North America rather than countries where the virus is known to be present.
The sudden and unexpected appearance of monkeypox simultaneously in several regions with no direct and immediate travel links to regions with a long history of monkeypox infection suggests that there may be undetected transmission for several weeks or more.

Description of the outbreak

As of June 8, 1,285 laboratory-confirmed cases and one probable case have been reported to WHO from 28 countries in four WHO regions where monkeypox is uncommon or not previously reported. This represents an increase of 505 laboratory-confirmed cases since the previous outbreak information bulletin on 4 June 2022, which reported 780 cases. As of June 8, 2022, no associated deaths have been reported in these four regions.

Among the cases reported in these regions, the majority of confirmed cases (87%) are from the WHO European Region (112). Confirmed cases have also been reported in the Americas (153), Eastern Mediterranean (14) and Western Pacific (6) regions. The number of cases fluctuates as new information is reported and becomes available daily and the data is verified according to the International Health Regulations (IHR 2005).

So far, clinical presentation The cases of monkeypox associated with this outbreak have been variable.

  • Many of the cases in this outbreak do not present the clinical picture traditionally described for monkeypox (fever, swollen lymph nodes, followed by a rash centered on the face and extremities).
  • The described atypical features include: the appearance of a few lesions or even one wound; Lesions that begin in the genital or perineal/perianal area and do not extend further; lesions that appear at different stages of development (asynchronous); Lesions appear before swollen lymph nodes, fever, malaise, or other symptoms appear.

The routes of sexual transmission are still unknown; While it is known that close physical contact can lead to transmission, it is unclear what role sexual body fluids, including semen and vaginal fluids, play in the transmission of monkeypox.

Two types of vaccines (ACAM-2000 and MVA-BN) are currently being deployed by some Member States to serve as prevention of close contact. Others may keep stocks of other types of vaccines (eg, LC16).

In addition, since the beginning of the year, 1,536 suspected cases have been reported in eight countries in the WHO African RegionOf these, 59 confirmed cases and 72 deaths. The ongoing discovery of the virus and reported deaths in some countries in the African region underscore the need to better understand the source and transmission dynamics and to provide people with the information and support they need to protect themselves and others in a variety of different contexts. In countries with a long history of monkeypox, more testing is needed to understand current and new sources of infection.

Source: World Health Organization (WHO)

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