External reproduction: causes, symptoms and treatment

Verified 06/23/2022 by PasseportSanté

Exogenous inbreeding is a term in medical terminology often used to qualify any diseases associated with excessive or chronic alcohol consumption. These may be symptoms of diabetes or diseases directly or indirectly related to alcoholism.

What is external reproduction?

An external term comes from the Greek exo (meaning “external”), Genoa (meaning “boy”) and osis (meaning “motive”, “cause”).

External reproduction refers to pathology by poisoning due to the consumption of a foreign body. In theory, it could be any type of poisoning (eg metal poisoning or food poisoning). But in practice, doctors often use the term to qualify any diseases associated with excessive or chronic alcohol consumption.

External reproduction refers in the broad sense:

  • Acute intoxication associated with excessive alcohol consumption (drunkenness, alcoholic coma, etc.);
  • Chronic diseases associated with alcoholism (malnutrition, chronic gastritis, liver failure, alcoholic cardiomyopathy, immune depression, cognitive disorders (Korsakoff syndrome), encephalopathy, neuropathy, stroke, myopathy, cancer, etc.);
  • Diseases indirectly related to alcoholism (head and accidental injuries, degeneration of the spinal cord, stroke, neuroinfections, disulfiram polyneuropathy, fetal alcohol syndrome);
  • Withdrawal syndrome due to alcoholism, etc.

What are the different exogenous genes?

Alcohol intoxication can lead to acute or chronic disorders.

sharp external

These are the direct effects of excessive alcohol consumption. The patient may undergo the following:

  • simple dregs (playful, alienating, incoherent notes);
  • delusional or pathological intoxication (behavioral disturbances, sometimes violence or danger, hallucinations, delusions);
  • convulsive intoxication (one generalized seizure during acute poisoning in an accidental drinker, not requiring antiepileptic therapy);
  • Alcoholic coma: In case of massive alcohol absorption, encephalopathy can occur in the form of a stage of collapse and then stupor, and finally alcoholic coma which can include signs of gravity (respiratory depression, hypothermia, hypotension, etc.) involving vital diagnosis Then require transfer to intensive care. Neurological complications are possible.
  • Hangover (headache, digestive disorders, fatigue, extreme thirst) or even fainting (do not mention the day after drunkenness).

chronic external

Chronic extrinsic diseases refer to all diseases caused by chronic alcohol consumption. The main alcohol-related diseases are:

  • cancers (upper gastrointestinal tract, esophagus, liver, breast, colorectal);
  • Cardiovascular diseases (arterial hypertension, angina pectoris, alcoholic cardiomyopathy, heart rhythm disturbances, stroke, etc.);
  • diseases of the liver and digestive system (steatosis, fibrosis or cirrhosis of the liver, gastritis, chronic pancreatitis);
  • Neurological diseases (cognitive disorders, memory loss, Korsakoff syndrome, alcoholic polyneuropathy);
  • malnutrition and undernutrition;
  • metabolic diseases and electrolyte disorders (hypoglycemia, hypertriglyceridemia, hyponatremia);
  • Bone, skin and joint disorders (gout, osteoporosis, exacerbation of rosacea);
  • Alcoholism and withdrawal syndrome (anxiety, sweating, agitation, confusion, insomnia, tremors, even convulsions).

What are the treatments for exogenous formation?

It is necessary to treat external diseases as well as their causes and this requires stopping alcohol intake or withdrawal in the case of chronic alcoholism.

Acute exogenous gene therapy

In case of severe alcohol poisoning, it is recommended to stop taking it immediately.

Symptoms of diabetes should subside over a period of hours. If a “hangover” occurs (the day after drunkenness), it is recommended to rest, drink plenty of water (risk of dehydration), treat headaches (with NSAIDs or paracetamol) and eat a balanced diet.

If an alcohol coma occurs, call 15 as soon as possible. While waiting for treatment, it is recommended that the patient be laid on his side in a safety lateral position to check his pulse and breathing and to be covered to prevent hypothermia.

In the hospital, management includes resuscitation, respiratory protection, blood gas analysis, and blood testing. In general, it is envisaged to go home 3 to 6 hours after your last alcohol intake.

Chronic exogenous gene therapy

In the case of a disease associated with chronic alcoholism, alcohol withdrawal must first be considered. A framework of psychotherapy (in addiction science), hospitalization, and medication are often necessary.

Three drugs currently have official marketing authorization to maintain abstinence in alcohol-based subjects:

  • acamprosate;
  • naltrexone;
  • disulfiram;

Acamprosate and naltrexone are first-line treatments that can be used as soon as possible after stopping alcohol consumption, with the goal of reducing craving for alcohol and thus reducing the risk of relapse.

In addition, the management of external diseases (as a result of chronic alcoholism) is also necessary. In the case of cancer, for example, chemotherapy or radiotherapy may be required.

Malnourished patients should be subject to lifestyle and dietary measures, a high-calorie diet and nutritional supplements. There are also specific treatments for disorders of the nervous system, digestive system, and even cardiovascular diseases.

What are the causes of exogenous genes?

The cause of infection outside is excessive or chronic consumption of alcohol.


Once alcohol enters the bloodstream, it has a direct effect on the central nervous system. We are talking about a state of intoxication from a blood alcohol level of about 1 to 2. In the hibernation stage (alcohol level from 2 to 3 ‰), the main functions are seriously disrupted.

Thus, the ability to respond is practically non-existent. From a blood alcohol level of 3 ‰, an adult can lose consciousness, fall into a coma and risk death. Then the body temperature drops significantly, breathing is impaired and respiratory paralysis can occur.

Chronic alcohol consumption

In the case of chronic alcoholism, the liver is the first organ affected, but it is not the only one: the nervous system is also very sensitive to it.

Alcohol is a notorious carcinogen, especially in the digestive system. In fact, the liver filters most of the alcohol circulating in the blood.

Liver deterioration consists of three stages:

  • steatosis;
  • Acute alcoholic hepatitis.
  • Cirrhosis (almost complete destruction of cells, which are replaced by scar tissue).

Liver atrophy and stops performing its work. When this organ malfunctions, a slow accumulation of toxins occurs, which also disturbs the activity of the brain.

In the long term, the main effect of alcohol is to slow down the activity of the central nervous system, sometimes causing irreversible nervous disorders.

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